Biosketch
I am responsible for the “Evolution of learning” project that aims at determining how the mechanisms underlying information processing and learning are shaped by evolution and how learning mechanisms affect individual and population performance in a changing environment.
My other tasks include the coordination of the research activities within the MARM group and, in particular, the coordination of programming activities, to assure consistent and comparable output across subprojects.
I obtained my PhD in 2003 at the University of Groningen for my work on the evolution of sex determining mechanisms. Afterwards I did research on mechanistic modelling of treatment effects in schizophrenia. Following couple of years I was a lecturer at the Hanze University of Applied Sciences in Groningen. I started working on the current project in the MARM group in March 2019.
Publications
2023 E, Weissing FJ, Kozielska M. Neural network models for the evolution of associative learning.
2023 Kozielska M, Weissing FJ. A neural network model for the evolution of learning in changing environments.
2016 Johnson, M., Kozielska, M., et al. Translational modeling in schizophrenia: Predicting human dopamine D2 receptor occupancy. Pharm Res 33: 1003-17
2014 Johnson, M., Kozielska. M, et al. Dopamine D2 receptor occupancy as a predictor of catalepsy in rats: a pharmacokinetic-pharmacodynamic modelling approach. Pharm Res 31: 2605-17.
2013 Pilla Ready, V. Kozielska, M., et al. Population pharmacokinetic-pharmacodynamic modeling of haloperidol in patients with schizophrenia using positive and negative syndrome scale. J Clin Psychopharmacol 33: 731-9
2013 Pilla Reddy, V., Kozielska, M., et al. Pharmacokinetic-pharmacodynamic modeling of antipsychotic drugs in patients with schizophrenia. Part I: The use of PANSS total score and clinical utility. Schizoph. Res 146: 144-52
2013 Pilla Reddy, V., Kozielska, M., et al. Pharmacokinetic-pharmacodynamic modeling of antipsychotic drugs in patients with schizophrenia. Part II: The use of subscales of the PANSS score. Schizophr Res 146: 153-61
2013 Kozielska, M., et al. Sensitivity of individual items of the Positive and Negative Syndrome Scale (PANSS) and items subgroups to differentiate between placebo and drug treatment in schizophrenia. Schizophr Re. 146: 53-8
2013 Pilla Reddy, V., Kozielska, M., et al. Modelling and simulation of placebo effect: application to drug development in schizophrenia. J Pharmacokinet Pharmacodyn 40: 377-88.
2012 Kozielska, M., et al. Pharmacokinetic-Pharmacodynamic modelling of the D2 and 5-HT2A receptor occupancy of risperidone and paliperidone in rats. Pharm Res 29: 1932-48
2012 Pilla Reddy, V., Kozielska, M., et al. Modelling and simulation of the Positive and Negative Syndrome Scale (PANSS) time course and dropout hazard in placebo arms of schizophrenia clinical trials. Clin Pharmacokinet 51: 261-75
2011 Johnson, M., Kozielska, M., et al. Mechanism-based Pharmacokinetic-Pharmacodynamic modelling of the dopamine D2 receptor occupancy of Olanzapine in rats. Pharm Res 28: 2490-504
2011 Pilla Reddy, V., Kozielska, M., et al. Structural models describing placebo treatment effects in schizophrenia and other neuropsychiatric disorders. Clin Pharmacokin 50: 429-50
2010 Kozielska, M., et al. Segregation distortion and the evolution of sex-determining mechanisms. Heredity 104: 100-12
2008 Feldmeyer, B., Kozielska, M. et al. Climatic variation and the geographical distribution of sex-determining mechanisms in the housefly. Evol Ecol Res 10:797-809
2008 Kozielska, M., et al. Are autosomal sex determining factors of the housefly (Musca domestica) spreading north? Genet Res 90:157-65
2006 Kozielska, M., et al. Sex ratio selection and multi-factorial sex determination in the housefly: a dynamic model. J Evol Biol 19: 879-88.
2004 Kozielska, M., et al. Good genes and the maternal effects of polyandry on offspring reproductive success in the bulb mite. Proc R Soc Lond B 271:165-70.